Alexander Rudensky

Puretech Health LLC (PureTech Ventures) is a venture capital subsidiary of PureTech Health Plc founded in 2000 by Daphne Zohar, Robert Langer and Ben Shapiro. The firm is headquartered in Boston, Massachusetts.

National Academy of Sciences operates as a private, nongovernmental institution that advises on issues related to science and technology. It provides independent, objective analysis and advice and conducts other activities to solve complex problems and inform public policy decisions. The firm also encourages education and research, recognize outstanding contributions to knowledge, and increase public understanding in matters of science. The company was founded on March 3, 1863 and is headquartered in Washington, DC.

Follica, Inc. develops therapies for hair follicle disorders. The firm provides an out-patient therapy coupled with an at-home system for the treatment of androgenetic alopecia (hair loss) and medical device development fields to develop and commercialize its product platform. The company was founded by Rox R. Anderson, George Cotsarelis, Vera Price, Daphne Zohar, David Steinberg, and Bernat Olle in 2006 and is headquartered in Boston, MA.

Alivio Therapeutics, Inc. develops therapies to treat inflammatory disorders through targeted disease immunomodulation. The company was founded by Robert S. Langer, Jeffrey Karp, John LaMattima, Brian Leuthner, Bennett Shapiro, Eric Elenko, Joep Muijrers, and Stephen Muniz and is headquartered in Boston, MA.

Cornell University is an educational institution that offers undergraduate and post graduate programs. It was founded in 1865 and is based in Ithaca, NY.

Enlight Biosciences LLC develops research tools for drug discovery and development. It offers patient-centric platforms that may impact all aspects of the connected health ecosystem from patient engagement and experience, to patient-focused research and development. The company was founded by Raju S. Kucherlapati, David Steinberg, Rakesh Kumar Jain, H. Robert Horbitz, and Sanjiv Sam Gambhir in July 2008 and is headquartered in Boston, MA.

PharmaLex GmbH engages in the provision of specialized services in the fields of development consulting, regulatory affairs, epidemiology and risk management, compliance, as well as quality management, particularly for the pharmaceutical, biotech, and medical device industries. These include providing technical and development support for product development, in-house management of clinical and analytical programs, establishment of pharmacology and regulatory services to ensure approval of pharmaceutical products in certain markets, development of decision-making tools for clinical trial recruitment, and study monitoring and program management. The company was founded in 1994 and is headquartered in Friedrichsdorf, Germany.

Rapport Therapeutics, Inc. engages in the discovery and development of transformational small molecule medicines for patients suffering from central nervous system disorders. It develops the RAP (receptor associated proteins) technology platform. The company was founded by Steven M. Paul and David Bredt in February 2022 and is headquartered in Boston, MA.

Juventas Therapeutics, Inc. provides regenerative therapies for cardiovascular disease. It is a clinical-stage biotechnology company developing a pipeline of factor-based regenerative therapies to treat life-threatening diseases. The company's product has been shown to protect and repair tissue following ischemic injury by recruiting the body's own stem cells to the damaged tissue. The company was founded by Rahul A. Aras and Marc S. Penn in 2007 and is headquartered in Cleveland, OH.

Michael Smith Laboratories provides biotechnology research and training services. It investigates genetics in human, animals and plants, fermentation, bioprocess engineering and bioinformatics. The company is headquartered in Vancouver, Canada.

The Canadian Institutes of Health Research is the federal health research financing organization in Canada. The non-profit company is based in Ottawa, Canada. The organization's main focus is to fund health research projects across the country.

Microbiome Insights, Inc. provides analysis and testing services for academic and industrial researchers. The firm’s services include experimental design consultation, sample extraction, nucleic acid processing and analysis as required (cdna generation, pcr, sequencing, etc.), basic data analysis, advanced data analysis, data and sample storage and submission to public databases. The company was founded by Malcolm C. Kendall, Barton B. Finlay and Bill Mohn in 2015 and is headquartered in Vancouver, Canada.

Boehringer Ingelheim (BIVF) is the venture capital arm of Boehringer Ingelheim International GmbH, itself a subsidiary of C.H. Boehringer Sohn AG & Co. KG. The firm was founded in 2010 and is headquartered in Ingelheim, Germany. It also has two US offices located in Fremont, California, and Cambridge, Massachusetts.

ArmaGen, Inc. engages in operation of a clinical stage biotechnology company focused on developing revolutionary therapies for severe neurological disorders. Its products include AGT-110-Brain-penetrating biologic tumor necrosis factor inhibitor (TNFI) for Alzheimer's disease, AGT-115-Brain-penetrating erythropoietin (EPO) for stroke, AGT-160-Brain penetrating anti-amyloid antibody (AAA) for Alzheimer's disease and AGT-181-Brain-penetrating iduronidase (IDUA) for Mucopolysaccharidosis (MPS) Type I (Hurler's syndrome). The company was founded by William M. Pardridge and Ruben J. Boado in 2003 and is headquartered in San Diego, CA.

Sentien Biotechnologies, Inc. develops cell-based therapy for critical care. It provides the Sentinel, a device that actively treats patients during a dialysis dose by supplementing patient blood with MSC-derived secretions. The company was founded by Brian Miller and Biju Parekkadan and is headquartered in Lexington, MA.

Tilos Therapeutics, Inc. designs and develops biotechnology products such as developing new treatments for cancer, fibrosis and autoimmune disease. It develops antibody therapeutics that target key immunological pathways, with a primary focus on regulatory T cells and regulation of effector cells. The company was founded by Howard L. Weiner in 2016 and is headquartered in Lexington, MA.

The Boston Consulting Group, Inc. engages in the provision of management consulting services. It specializes in automotive and mobility; biopharmaceuticals; consumer products; education; oil and gas; power and utilities; engineered products and infrastructure; financial institutions; and health care payers, providers, and services. It offers big data and advanced analytics; change management; client learning and enablement; and corporate development and financial services. The company was founded by Bruce Doolin Henderson in 1963 and is headquartered in Boston, MA.

Part of Fair Isaac Corp., Vertex Partners is a consulting firm based in Boston, MA. The company provides consulting services in various fields such as strategy/IT and recruiting. Vertex Partners combines the knowledge of many companies to create new ventures and supports initiatives related to innovation and new business creation. Luce, a recruitment firm, is a subsidiary of Vertex Partners. Accuchain, a company that modernizes HR recruitment software, is also a part of Vertex Partners. The company was founded by Paul J. Bascobert. Vertex Partners was acquired by Braun Consulting, Inc. on May 11, 1999.

Knode, Inc. develops and delivers web-based life science solutions for accessing experts and their content. It offers solutions for project team formation, post-merger integration, collaborations, business development, and decision-making applications. The firm provides services to pharmaceutical companies, academic institutions and researchers. The company was founded in 2011 and is headquartered in Boston, MA.

IMRSV, Inc. provided a platform for audience measurement. The company was founded in 2009 by Jill Miller, Jason Sosa and Akshay Chavan and was headquartered in New York, NY.

Entrega, Inc. develops oral drug delivery technologies. The firm’s platform enables novel applications in a variety of fields, such as disease management and tracking in the burgeoning mobile health arena. Its proprietary technology seeks to solve the oral delivery problem with an engineering solution that protects the payload and delivers biological molecules, drug substances and nanoparticles. The company was founded by Samir Mitragotri in 2010 and is headquartered in Boston, MA.

Part of PureTech Health Plc, Commense, Inc. provides biotechnical research services. The company is based in Boston, MA. Edward J. Stewart has been the CEO of the company since 2018.

Longwood Fund Management LLC (Longwood Fund) is a venture capital firm founded in 2010 by Christoph H. Westphal, Michelle Detwiler and Richard H. Aldrich. The firm is headquartered in Boston, Massachusetts.

Be Biopharma, Inc. develops engineered B cells as a new category of cellular medicines. The company was founded by David Steinberg, Aleks Radovic-Moreno and Lea Hachigian and is headquartered in Cambridge, MA.

Rectify Pharmaceuticals LLC is a biotech company that is developing positive functional modulators (PFMs) to address the underlying cause of serious ABC transporter-mediated diseases. The company is based in Cambridge, MA and was founded by Jonathan Moore. The company's team includes Xiaobing Li as Chief Development Officer, Robert Hughes as Executive Vice President of Drug Discovery and Preclinical Development, and Leif-Ann Tuohey as Senior Vice President and Head of Business Development. The company has received $100 million in Series A financing from Atlas Venture, Omega Funds, Forbion, and Longwood Fund. The CEO is Rajesh Devraj, who is also a venture partner at Atlas Venture.

Photys Therapeutics, Inc. is a company based in Cambridge, MA that was founded by Longwood Fund and Dr. Amit Choudhary of Brigham and Women's Hospital and the Broad Institute of MIT and Harvard. The company is advancing phosphorylation inducing chimeric small molecules (PHICs), a proprietary new class of bifunctional medicines that direct and repair protein phosphorylation to treat a range of diseases including cancer, immune, metabolic, and rare diseases. PHICs enhance the pairing of specific kinases with disease target proteins, inducing precise phosphorylation at native and/or non-native sites, modulating key functions including activation, stabilization, trafficking, localization, phospho-antigen presentation, inactivation, degradation, and interactions of proteins. The company's approach unlocks diverse classes of targets, developing a new class of medicines for precise control of protein function. The company was founded by Amit Choudhary, David Steinberg, Edward Holson, Lizzie Ngo. David Steinberg has been the CEO since incorporation.