Sanford J. Madigan

Sova Pharmaceuticals, Inc. engages in the discovery and development of human therapeutic drugs. It provides internal clinical plan on therapies supported by the mechanism, our preclinical findings, and the development of compounds reported to act on the molecular targets of H2S that include postherpetic neuralgia, chemotherapy induced peripheral neuropathic pain (CIPN pain) and diabetic neuropathy. The company’s pre-clinical findings support large-market indications, such as osteoarthritis, rheumatoid arthritis, neuropathic pain and migraine, that we would seek to develop with a strategic partner. The company was founded by Gary W. Pace and Solomon Snyder in 2010 and is headquartered in La Jolla, CA.

Ankasa Regenerative Therapeutic, Inc. operates as a biopharmaceutical company. It develops strategies to improve tissue healing by exploiting the potential of stem cell reactivation. The firm develops a proprietary formulations of a potent WNT stem cell activator with the potential to accelerate tissue healing in a broad range of degenerative conditions affecting bone, cartilage, skin, muscle, vasculature, and the central nervous system. The company was founded on September 9, 2014 and is headquartered in La Jolla, CA.

CadheRx Therapeutics, Inc. develops therapeutic antibodies for the treatment of solid tumors. The firm's soluble E-cadherin (sEcad) levels are increased in many epithelial cancers and result in increased tumor cell proliferation, migration, invasion and angiogenesis. The company was founded by Sandy J. Madigan and is headquartered in La Jolla, CA.

Calporta Therapeutics, Inc. engages in developing small molecule agonists. It develops selective small molecule agonists of TRPML1 (transient receptor potential cation channel, mucolipin subfamily, member 1) for the treatment of Niemann-Pick C Disease (NPC) and other lysosomal storage diseases. The company was founded by Haoxing Xu and is headquartered in La Jolla, CA.

Nerio Therapeutics, Inc. provides biotechnology services. The company is headquartered in La Jolla, CA.

Anexigen, Inc. is a biotechnology company developing novel methods and compositions to combat existing and burgeoning antimicrobial threats. The company was founded by Sanford Madigan and Sergio Duron and is headquartered in La Jolla, CA.

Silarus Therapeutics, Inc. develops therapeutics targeting erythroferrone for the treatment of iron deficiency and iron overload disorders. The company was founded by Tomas Ganz, Sanford J. Madigan, and Elizabeta Nemeth in May 19, 2014 and is headquartered in La Jolla, CA.

X-Ceptor is a privately held biopharmaceutical company focusing on research in the rapidly developing field of orphan nuclear receptors that serve as the molecular targets for the discovery of novel small molecule pharmaceutical products for the treatment of human diseases. X-Ceptor has developed an integrated approach to drug discovery drawing from their in-house expertise in biology, chemistry and high-throughput screening. X-Ceptor's advantage lies in its understanding of orphan nuclear receptors and their signaling pathways, as well as its proprietary ability to employ these orphan nuclear receptors in transcriptional and biochemical based assays to discover novel therapeutic agents