Dear Freddie

Part of BlackRock, Inc., BlackRock Investments LLC is a brokerage services provider. The company is based in New York, NY. The company was founded in 1994. Abigail Tate Reynolds has been the CEO of the company since 2006.

PricewaterhouseCoopers Corporate Finance LLC provides financial advisory services. The company is headquartered in Chicago, IL.

McKinsey & Co., Inc. provides management consulting services. It specializes in design, marketing and sales, analytics, operations, transformation and restructuring, risk, strategy and corporate finance, and sustainability and resource productivity. The company was founded by James O. McKinsey in 1926 and is headquartered in New York, NY.

Duke University is an academic university that offers undergraduate, graduate and professional programs. It also has publications and research services. The university was founded in 1838 and is headquartered in Durham, NC.

Ruffer LLP is the investment management subsidiary of Ruffer Management Ltd. in Great Britain. The firm was founded as Ruffer Investment Management Ltd. in 1994 by Jonathan Ruffer, Jane Tufnell, and Earl Ferrers. In 2004, they transferred their investment business to Ruffer LLP. Headquartered in London, Ruffer manages assets and funds on a discretionary basis for private and institutional clients including trusts, charities, pension funds, family offices, corporations, investment companies and insurance companies. Ruffer is a responsible investor that fully integrates environmental, social and corporate governance (ESG) issues into their investment process.

The Boston Consulting Group, Inc. engages in the provision of management consulting services. It specializes in automotive and mobility; biopharmaceuticals; consumer products; education; oil and gas; power and utilities; engineered products and infrastructure; financial institutions; and health care payers, providers, and services. It offers big data and advanced analytics; change management; client learning and enablement; and corporate development and financial services. The company was founded by Bruce Doolin Henderson in 1963 and is headquartered in Boston, MA.

Downing Ventures (Downing Ventures) is an independent venture capital firm founded in 1986. The firm is headquartered in London.

Credit Suisse Securities (Europe) Ltd. (Credit Suisse Europe) is the Great Britain-based brokerage subsidiary of Credit Suisse Investment Holdings (UK), itself a subsidiary of Credit Suisse Group AG (SWX: CSGN) in Switzerland. The firm was founded in 1966 and formerly known as Credit Suisse First Boston (Europe) Ltd. Headquartered in London, Credit Suisse Europe arranges financing in international capital markets, provides financial advisory services and acts as a dealer in securities, derivatives and foreign exchange on a principal and agency basis for corporate and institutional investors.

UBS AG (London Branch) is the Great Britain-based brokerage subsidiary of UBS AG, ultimately held by UBS Group AG (SWX: UBSG) in Switzerland. Headquartered in London, the firm was founded in 1998 and provides nimble, innovative and bespoke access to solutions, from market and insight tools, to trading strategies and execution for private, institutional and corporate clients worldwide, as well as private clients in Switzerland. They distribute, trade, finance and clear cash equity and equity-linked products. The firm also structures, originates and distributes new equity and equity-linked issues.

BlackRock Investment Management (UK) Ltd. (BIM-UK) is an investment management firm headquartered in London, UK. The firm is a subsidiary of BlackRock Finance Europe Ltd., ultimately owned by BlackRock, Inc. (NYSE: BLK) in the US. BIM-UK was founded in 2006 following the merger of Merrill Lynch Investment Managers and BlackRock. In 2009, BlackRock merged with Barclays Global Investors, including the iShares exchange traded funds business. The combined firm operates under the BlackRock name and has retained the iShares brand. BIM-UK manages a family of mutual funds and acts as sub-advisor to other mutual and pension funds. They also offer alternative investments and managed accounts for individual and institutional clients.

Close Asset Management Ltd. (Close AM) is the asset management subsidiary of Close Asset Management Holdings Ltd., itself a subsidiary of Close Brothers Group plc (LSE: CBG, ADR: CBGPY) in Great Britain. The firm was founded in 1982 and does business as Close Brothers Asset Management. Headquartered in London, Close AM provides a bespoke investment management service to private clients, trusts and corporates.

Forbion Capital Partners Management Holding BV (Forbion) is a Netherlands-based venture capital firm which was founded by Bart Bergstein. Headquartered in Naarden, the firm specializes in late-stage and early-stage clinical development programs to optimize the commercial potential of their investee company's technologies.

Simmons & Co. International Ltd. (Private Equity) (Simmons & Co. International) is a private equity subsidiary of Simmons & Co. International Ltd. founded in 1974. The firm is headquartered in London.

Valco Investments Ltd (Valco) is a private equity firm. The firm is headquartered in London.

The Boston Consulting Group Ltd. provides management consulting services. Its capabilities includes corporate development and finance, postmerger integration, digital economy, risk management, globalization, strategy, innovation, growth, sustainability, marketing and sales, technology, operations, turnaround and transformation and people and organization. The company was founded in 1963 and is headquartered in London, the United Kingdom.

Augmentum Capital LLP (Augmentum Capital) is an independent venture capital firm founded in 2009 by Tim Levene and Richard Matthews. The firm is headquartered in London.

Ruffer AIFM Ltd. is an alternative investment manager headquartered in London, UK. The firm was founded in 2013 and is a subsidiary of Ruffer LLP, which is owned by Ruffer Management Ltd. Ruffer AIFM provides investment management services for institutions, pension funds, charities, financial planners and private clients.

OMass Therapeutics Ltd. develops native mass spectrometry platform The company was founded by Dame Carol Robinson and is headquartered in Oxford, the United Kingdom.

Meridian Street Capital LLC (Meridian Street Capital) is a venture capital firm founded in 2016. The firm is headquartered in New York.

SB Investment Advisers (UK) Ltd. is a Private Equity firm, a subsidiary of SoftBank Group Corp. founded in 2016 by Masayoshi Son. SB Investment Advisers (UK) Ltd. is headquartered in London, UK.

Human Immunology Biosciences, Inc. is a company based in South San Francisco, CA. Human Immunology Biosciences, Inc. was founded by Travis Murdoch, who has been the CEO since incorporation.

Third Rock Ventures LLC (Third Rock Ventures) is a venture capital firm founded in 2007 by Mark Levin, Robert Tepper, Kevin Starr and Nick Leschly. The firm is headquartered in Boston, Massachusetts.

Arceau Capital Ltd (Arceau Capital) is a venture capital firm founded in 2020 by Louis D'Origny. The firm is headquartered in Miami, Florida.

Cylon Ltd.(Cylon) is an accelerator & incubator and a venture capital firm founded by Alexander Rupert van Someren, Jonathan Luff and Grace Cassy in 2015. The firm is headquartered in London, UK.

Purespring Therapeutics Ltd. provides biotechnological research and experimental development services. The company was founded on April 1, 2020 and is headquartered in London, the United Kingdom.

Part of Gas Sensing Solutions Ltd., Cambridge Respiratory Innovations Ltd. develops and manufactures medical devices. The private company is based in Swavesey, UK.

Nina Capital SGEIC SA (Nina Capital) is a venture capital firm founded in 2019 by Marta Gaia Zanchi. It is headquartered in Barcelona, Spain.

contextflow GmbH provides a search engine which allows radiologists to search for visually similar images from a hospital's database. It provides technology for radiologists, radiology departments, hospital groups, university hospitals and also for the extension for existing image archives. The company was founded by Markus Holzer and is headquartered in Vienna, Austria.

EarlySight SA engages in the development, production, and marketing of imaging solutions for the medical and life science sectors. It focuses primarily on the development of an eye camera for the monitoring of the tissue degenerative process associated with retinal diseases. The company was founded by Timothé Laforest, Mathieu Kunzi, Christophe Moser, and Francine Behar-Cohen in 2019 and is headquartered in Lausanne, Switzerland.

Neucruit Ltd. develops a patient management platform for the healthcare industry. The company is based in London, UK. The British company was founded in 2019. Livia Ng has been the CEO of the company since 2019.

Karius, Inc. operates clinical and medical research laboratory. It enables clinicians to diagnose infectious diseases by detecting the DNA of pathogens from a standard blood draw. The company was founded by Michael Kertesz and Tim Blauwkamp and is headquartered in Redwood City, CA.